15 Best Patient Portal Software For Medical Use in 2025

Are you looking to implement  a patient portal in your healthcare organization? We've compiled a list of leading vendors' best Patient Portal Software solutions. No sponsored listings here. Our list is created based on research on software marketplaces and a thorough analysis of provider offerings. Check our post to find the optimal Patient Portal Software that meets your business needs.

Patient Portals: Off-the-Shelf vs Custom Development

The right healthcare portal or app can not only help you store and manage information like patient data, lab analysis results, and medical history. It also helps your organization improve its communication with patients. By enabling a safe digital space for your patients, you build trust in your services, increase patient satisfaction, and, therefore, your healthcare organization's profitability. So where to find one? 

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Patient Portal software implementation can be approached in two ways:

• Off-the-shelf patient portals. These are ready-made SaaS portals which you can sign up for your organization.

• Custom patient portal development. You can develop patient portal software from the ground up, including custom functionality and workflow to match your domain.

As you will see, commercial patient portal software includes many features and often is part of an electronic health records (EHR) suite. Stand-alone patient communication platform offerings are also available and can be a good fit for specific use cases, such as dental clinics or behavioral practices.

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If none of the solutions fits you, consider partnering with a software development provider like NEKLO to get a custom patient portal.

Patient Portal Software Review Criteria

We based our research on the following criteria when selecting among the patient access system providers. Below, we’ve included an explanation of why each criterion matters.

• Digital Health Portals For Medical Purpose
• HIPAA-Compliance
• Patient Engagement and Communication Functionality
• Customization Options
• Platform Support
• User-friendliness
• Customer Feedback & Reviews

Best Patient Portal Software Compared: Overview

Patient Portal Software: Medical Use & HIPAA

In our comparison, we reviewed patient portal vendors that provide software intended for medical purposes. Such software is designed specifically for patients and medical practitioners to help manage health data related to patient monitoring, treatment, and consultation.

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Patient and medical portal software has the highest security requirements and must comply with HIPAA regulations. 

• HIPAA Compliance: Ensures compliance with the Health Insurance Portability and Accountability Act (HIPAA) in the U.S.
• Multi-Factor Authentication: Requires additional authentication steps to verify user identity.‍
• Data Encryption: Uses advanced encryption methods to protect sensitive health data.

Patient Portal Software: Must-Have Functionality

Health portal systems vary in functionality. Some solutions focus on simplicity, providing basic tools for patients to track and manage their appointments. Others extend their offering with advanced functionality like virtual consultations, prescription management, and an extensive education knowledge base. While these features are great for patient engagement, they might not be necessary for your particular use case. 

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Consider the market trend for patient portal software. In 2021, 71% of healthcare organizations in the United States enabled patients to access lab results through their medical portals. Additionally, nearly 70% offered the capability for patients to schedule appointments directly via the portal.

In our post, we’ve selected vendors that either provide a stand-alone patient portal solution or let you integrate such functionality as part of the EHR suite. We selected patient engagement platforms that let users create accounts, view their information but manage it, and have two-way communication with medical practitioners, e.g., messaging and telemedicine app features. With this in mind, we’ve highlighted the following most important features of patient portal software:

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• Client Portal: An online portal through which end users can access the system, manage tasks, or obtain information.
• Appointment Scheduling: Schedule appointments and bookings via a calendar.
• Billing & Invoicing: Create, manage, and send invoices or bills to customers. Manage billing and payments for a healthcare provider.
• Document Management: Store, manage, and track all electronic documents in a centralized location.
• Health Records: Gaining access to confidential health documents and information.
• Secure Messaging: Exchange messages in a secure and encrypted manner.
• Telemedicine: Set up virtual meetings with patients in real time via video conferencing.

Customization and Integration Options

Customization capabilities in patient portals are essential as they let your healthcare organization tweak the software to match your brand identity. Above that, you can configure the patient workflows and adjust some features so that the software ideally matches your users’ needs.

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Last but not least, it’s important to check the integration capabilities of your patient portal software. To streamline workflows, you can integrate with healthcare CRMs to better track your patients or pharmacy management software if you want your patients to seamlessly manage their medicine prescriptions.

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Customization Options To Look For: 

• Branding (logos, colors)
• Tailored patient workflows 
• Personalized messages, templates
• Personalized care plans
• Integration with other healthcare applications (CRM, ERM, EHR)

Patient Portal Software: Platform Support

Platform support is a crucial factor in determining where you can deploy your patient portal software. It's important to consider the preferences of your patients. Some may feel more comfortable accessing their information using a computer, making web-based platform support a priority. Others may prefer to access their health-related data on the go, which is where mobile deployment options become essential. 

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Which option is best? Ideally, the patient portal software should be available cross-platform with the following deployment options:

• Web-Based: Cloud, SaaS
• Desktop: Chromebook, Mac, Windows, Linux
• On-Premise: Windows/ Linux
• Mobile: Android, iPhone, iPad

Patient Portal Software: User Experience (UX) and Interface (UI)

User experience (UX) defines how easily patients can get around in your healthcare portal software. It defines if all the features are accessible at a glance, how natively you can navigate among sections and tabs, and whether you can leave feedback if you have any troubles with the software. These are the basic criteria for any software UI; however, for healthcare solutions, with patient portals being no exception, you may also check the following UX features:

• Quick access to health data
• Convenient patient dashboard
• Easy and instant messaging/calling with healthcare providers
• Multi-language support
• Compliance with accessibility standards
• Assistive technology integration (voice recognition, text-to-speech, etc.)

User interface (UI) is something that you shouldn’t ignore either. Patient portals with modern and clean layouts build trust and encourage the users to stick to the software. Outdated and poorly designed ones spoil the experience. 

Top 15 Patient Portal Software Vendors

Now, let’s review the best patient engagement platforms available in the market. We’ve highlighted their features, best-fit use cases and listed their pros and cons. 

SimplePractice is a leading practice management software specifically designed for health and wellness professionals, including therapists, counselors, and social workers. The platform offers a client portal with all the must-have features like billing, appointment management, secure messaging, and more. Founded in 2012, SimplePractice serves over 100,000 practitioners and is known for its intuitive interface and comprehensive feature set. The software is compliant with HIPAA regulations.

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Patient Portal Features:

• Online appointment scheduling
• Secure messaging
• Document sharing
• Telehealth capabilities
• Automated appointment reminders
• Billing and invoicing
• Measurement-based care tools
• Health records access
• iOS, Android app support

Best Suited For: Mid-size and large health organizations, therapists, mental health and wellness practitioners

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Pros:

• User-friendly interface
• Comprehensive telehealth functionality
• Strong focus on mental health and wellness practices
• Secure and compliant communication

Cons:

• Limited customization options for EHR functionality

Price: From $14.50 to $49.50 /month

EHR YOUR WAY is a customizable electronic health record, practice management, and patient portal software tailored to meet the needs of behavioral health, addiction treatment, and other healthcare providers. Founded in 2006, the platform is designed to streamline clinical workflows, improve patient care, and enhance operational efficiency. EHR YOUR WAY offers a range of features and allows for extensive customization to fit the specific requirements of different practices. The software is ONC-certified and compliant with HIPAA regulations.

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Features:

• Customizable EHR templates
• Appointment scheduling
• Billing and invoicing
• Secure messaging
• Document management
• Telehealth integration
• Automated reminders
• Reporting and analytics
• ePrescribing
• Mobile app support

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Best Suited For: Behavioral health professionals, addiction treatment centers, mental health clinics, group practices

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Pros:

• High level of customization
• Comprehensive feature set tailored for behavioral health
• Efficient scheduling and billing integration
• Strong focus on reporting and analytics
• Secure and compliant communication

Cons:

• Customization may require a longer setup time and additional costs
• Pricing may be high for small practices

Price:

Per request, min $800/month

Jane is an all-in-one practice management software designed for health and wellness professionals. It also offers a robust health portal system with secure messaging and telehealth capabilities, all accessible via a user-friendly interface. Launched in 2012, the Jane app offers a comprehensive suite of features to streamline administrative tasks, enhance patient engagement, and improve overall practice efficiency. The platform is fully HIPAA, PIPEDA, and GDPR-compliant.

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Features:

• Online booking
• Charting and clinical notes
• Telehealth integration
• Billing and invoicing
• Secure patient messaging
• Appointment reminders
• Client profiles
• Health records access
• Mobile app support
• Reporting and analytics

Best Suited For: Mental health practitioners, group practices, healthcare organizations with key focus on in-person interactions

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Pros:

• Intuitive and easy-to-use interface
• Comprehensive feature set for diverse health and wellness practices
• Efficient online booking and telehealth functionality

Cons:

• Limited customization options compared to some competitors
• Pricing can be complex and high for small practices

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Price: From $54/month to $99/month 

MidexPRO is a specialized practice management software with a patient portal designed for healthcare professionals in the UK. It offers a range of features to streamline administrative tasks, manage patient records, and enhance practice efficiency. You can integrate the MidexPRO client portal link into your website or distribute it via email to clients and patients. Other options include Mail Chimp campaigns and social media sharing. The software is designed to integrate seamlessly into UK healthcare settings, ensuring compliance with local regulations and standards. Secure messaging and HIPAA compliance are included. 

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Features:

• Appointment scheduling
• Patient records management
• Clinical notes and charting
• Billing and invoicing
• Prescriptions and medication management
• Reporting and analytics
• Secure messaging
• Mobile app support

Best Suited For: Healthcare facilities in the UK

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Pros:

• Tailored specifically for healthcare professionals in the UK
• Integration with NHS systems for seamless data exchange
• Mobile app for convenient access

Cons:

• Limited availability outside of the UK market
• May require initial training for new users to fully utilize all features

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Price: 30-day free trial, per request

Benchmark Solutions Practice Management is a comprehensive software suite designed for healthcare practices of various sizes. Developed by Benchmark Systems, a company with over 35 years of experience in healthcare technology, this platform integrates practice management, electronic health records, and health portal system. The patient portal offered by Benchmark Solutions comes as part of the suit and focuses more on the management aspect rather than engagement. However, Benchmark can be your go-to choice if you’re looking for a robust appointment scheduling, reminder, and billing tool for your patients.

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Patient Engagement Features:

• Patient Onboarding and medical profiling 
• Appointment Scheduling
• Appointment Reminders 
• Reporting templates about your practice’s day-to-day operations
• Medical billing 
• Customizable dashboards

Best Suited For: Medical practices of various specialties (e.g., primary care, specialty clinics)

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Pros:

• Powerful all-in-one EHR suit
• Dedicated support and training resources from Benchmark Systems

Cons:

• Patient engagement functionality is limited compared to other providers

Price: per request

My Clients Plus is a medical portal software designed for behavioral health professionals, including therapists, counselors, psychologists, and social workers. Operating since 2007, the client base includes thousands of practitioners in the behavioral health and therapy fields. My Clients Plus provides a comprehensive solution to manage scheduling, billing, and patient records. The platform includes a HIPAA-compliant patient portal that enhances engagement and communication.

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Patient Communication Features:

• Online appointment scheduling
• Secure messaging between providers and patients
• Access to treatment plans and progress notes
• Telehealth capabilities
• Appointment reminders
• Billing and invoicing integration
• Document and file sharing
• Customizable intake forms
• Mobile app for iOS and Android devices

Best Suited For: Behavioral health professionals

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Pros:

• Comprehensive patient access system 
• User-friendly interface with customizable options
• Integration with billing and telehealth services

Cons:

• Customization options may be limited compared to larger EHR systems

Price: $29/month per provider, add-ons available for separate payment

Carepatron is a modern platform designed to enhance patient care management and streamline healthcare operations. Developed with a focus on user experience and clinical efficiency, Carepatron integrates practice management, EHR, and patient engagement tools into a unified platform. Their healthcare portal solution stands as a telehealth platform with strong emphasis on virtual care.

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Patient Portal Features:

• Online appointment scheduling
• Secure messaging between patients and providers
• Access to personal health records and treatment plans
• Telehealth capabilities for virtual consultations
• Patient education resources
• Clinical notes
• Secure payments
• Mobile app for iOS and Android devices

Best Suited For: Healthcare providers across various specialties (e.g., primary care, specialized clinics, outpatient facilities)

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Pros:

• Comprehensive patient engagement features including scheduling, messaging, and health record access
• User-friendly interface 
• Customizable workflows and templates to fit different practice needs
• Cost-effective for small practices

Cons:

• Initial setup and training may be required for optimal use

Price: Free to $19/month for organizations

Theralytics is a specialized practice management and patient engagement software for ABA practices. The platform integrates comprehensive tools for managing clinical workflows, scheduling, billing, and patient communications. Theralytics' patient portal feature is tailored to enhance patient engagement and streamline administrative tasks, providing secure access to health records, appointment scheduling, and communication tools. It aims to optimize the therapeutic process by improving care coordination and patient outcomes through efficient practice management solutions.

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Features:

• Online appointment scheduling
• Document management
• Secure messaging between patients and providers
• Billing and invoicing integration
• Reporting on payroll, accounts receivable, session audits, RBT supervision
• Behavioral data tracking such as frequency, duration, rate, ABC, partial interval
• Mobile app for iOS and Android devices

Best Suited For: ABA practices, mental health professionals

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Pros:

• User-friendly interface for efficient practice management
• Integrated telehealth capabilities for convenient virtual sessions
• Mobile app support for on-the-go access to patient information

Cons:

• Integration capabilities with other healthcare systems may vary

Pricing: $15-25 per client/month, no annual contract required

Healee is a patient engagement platform and telemedicine solution designed to facilitate communication between patients and healthcare providers. It offers a user-friendly interface that integrates scheduling, messaging, and virtual consultations. Healee's patient portal provides secure access to medical records, appointment management, telehealth services, and HIPAA-compliant video consultations. The platform is designed to cater to healthcare providers seeking efficient telemedicine solutions combined with patient engagement tools.

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Patient Portal Features:

• Patient scheduling
• E-prescription, payment, sms/email notifications
• Calendar management
• Telehealth
• Patient intake
• Patient communication
• Integrations: EHR, ERM, E-prescribing, Drug information, Wearable devices, Conditions information

Best Suited For: Healthcare providers across various specialties (e.g., primary care, specialized clinics), practices focused on telemedicine and virtual care delivery

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Pros:

• Comprehensive electronic health portal 
• Extensive integrations support
• User-friendly interface designed for ease of use by both patients and providers
• Convenient virtual consultations

Cons:

• The onboarding may be consuming to some users

Pricing: per request

MediOffice is a practice management software designed to streamline administrative tasks and enhance patient care delivery for healthcare practices in the UK. Developed with a focus on efficiency and user-friendliness, MediOffice integrates scheduling, billing, and patient management functionalities into a unified platform. The patient portal feature offered by MediOffice aims to improve patient engagement by providing secure access to health records, appointment scheduling, and communication tools between patients and healthcare providers. The platform is tailored to meet the specific needs of healthcare practices looking to optimize operational workflows and enhance patient satisfaction.

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Patient Portal Features:

• Diary management and appointment scheduling 
• Digital health portal 
• Digital dictation 
• Invoicing and debt management
• Mobile apps for the practice and patient
• Reporting
• Integration with Healthcode
• Automated patient review requests​
• Task management
• Document generation and workflow​
• Automated reminders​

Best Suited For: Healthcare practices in the UK, including general practitioners, specialists, and outpatient facilities

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Pros:

• Strong focus on private practices
• Comprehensive features including scheduling, messaging, and health record access
• Secure and compliant with healthcare regulations (GDPR compliance for UK practices)
• Integrated telehealth capabilities
• Mobile app support 

Cons:

• Customization options may be limited compared to larger EHR systems

Pricing: £99 + VAT per month/doctor 

My Best Practice is a robust practice management and patient engagement software tailored for healthcare providers seeking to streamline operations and enhance patient care delivery. Launched with a focus on integrating advanced technology with healthcare needs, My Best Practice offers a versatile patient portal that facilitates communication between patients and doctors. With a user-centric approach, the platform aims to meet the diverse needs of healthcare practices, ranging from individual practitioners to larger healthcare facilities.

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Features:

• Appointment schedulers, billers & bookkeepers
• Clinical notes & treatment plans
• Client portal
• Appointment reminders
• Intake forms
• Online payments
• Custom surveys
• Telehealth
• E-Scripts
• Insurance billing
• Mobile app

Best Suited For: suitable for practices of different sizes and speciality focus

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Pros:

• Comprehensive feature set tailored for healthcare workflows
• Scalable with add-on features
• User-friendly interface designed to optimize user experience
• Integration capabilities with existing healthcare IT systems

Cons:

• Potential complexity in initial setup and configuration

Pricing: $39/month for the first professional, $19/month per additional professional

Legwork, developed by Planet DDS, is a comprehensive patient engagement and communication software tailored specifically for dental practices. Founded in 2003, Planet DDS has been a pioneer in cloud-based dental practice management solutions. The company serves thousands of dental practices across North America. Legwork patient management software integrates advanced tools to automate communication, track appointments, and facilitate marketing efforts.

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Patient Portal Features:

• Automated patient reminders and notifications
• Online appointment scheduling with real-time availability
• Access to health records, treatment plans, payment history, and educational resources
• Two-way messaging between patients and dental practices
• Integration capabilities with leading dental practice management software
• Mobile-friendly platform 

Best Suited For: Dental practices

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Pros:

• Supports practice growth through targeted marketing and reputation management
• Integrates seamlessly with existing dental practice management systems

Cons:

• Initial setup and training may be required to maximize utilization of all features
• Integration compatibility may vary with different practice management software solutions

Pricing: per request

Mend is a versatile telehealth and patient access system that caters to healthcare providers seeking to level up their service through virtual care. Founded in 2014, Mend has established itself as a leader in the telehealth industry. The platform integrates with existing EHR and practice management systems, so you can implement a well-rounded set of tools to manage your workflows. It also supports both scheduled and on-demand virtual visits, so you can cater to various patient care scenarios.

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Features:

• HIPAA-compliant video visits with high-definition audio and video
• Secure messaging for confidential patient-provider communication
• Automated appointment scheduling and reminders to reduce no-shows
• Patient intake forms and consent management for streamlined onboarding
• Billing and payment processing capabilities for efficient financial transactions
• Integration with leading EHR systems to consolidate patient data
• Customizable workflows and templates to adapt to diverse practice needs
• Advanced analytics and reporting tools for performance monitoring and improvement

Best Suited For: a wide range of hospitals, clinics, urgent care centers, and specialty practices looking for extend their service to virtual care

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Pros:

• Robust telehealth capabilities
• High-quality video and secure messaging
• Customizable features and workflows
• Well-rounded training resources for effective implementation

Cons:

• Dependence on Internet connectivity may impact the reliability of virtual visits

Pricing: per request

Pabau offers a comprehensive client portal designed to streamline communication and enhance interaction between healthcare providers and their clients. This platform is tailored for healthcare and aesthetic practices, providing tools that improve patient engagement, simplify administrative tasks, and optimize practice management. Pabau's client portal integrates various features for efficient communication, appointment management, and access to patient information.

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Patient Portal Features:

• Online Appointment Scheduling
• Digital Client Records
• Customisable Consent Forms
• Automated Pre/Aftercare Emails
• SMS/Email Appointment Reminders
• Integrated POS system
• Deposits & No-show protection
• Before and After Photos
• Track and view bookings, treatments and invoices
• Multiple Integrations
• Video Conferencing
• Injection Plotting

Best Suited For: suitable for practices of different sizes and speciality focus

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Pros:

• Comprehensive electronic health portal
• User-friendly UX and sleek UI
• Seamless integration with Pabau's practice management software for unified operations
• Secure messaging and compliance with data protection regulations

Cons:

• Initial setup and training may be required for effective utilization of all features
• Dependence on Internet connectivity for real-time interaction

Pricing: Starting from $28 /month for one user and less than 50 clients

BestoSys is a cloud-based practice management and patient communication software tailored for dental practices. Medical professionals can use it to handle administrative tasks, enhance patient communication, and improve overall efficiency. Patients can manage appointments, track records, billing, and more, all within a user-friendly interface. The software is designed to simplify workflows and enhance patient care delivery while ensuring compliance with HIPAA regulations for data security.

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Features:

• Online appointment scheduling
• Patient records management
• Treatment planning and charting
• Billing and invoicing
• Insurance management
• Patient communication tools
• Reports and analytics
• Mobile app support
• Integration with dental imaging systems

Best Suited For: Dental practices and clinics

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Pros:

• Tailored specifically for dental professionals' needs
• Easy-to-use interface designed for dental workflows
• Comprehensive feature set including treatment planning and dental imaging integration
• Mobile app for patients 

Cons:

• Limited customization options compared to larger EHR systems

Price: per request

How To Choose the Best Patient Portal Software for Your Organization

Choosing the best patient portal software requires careful consideration and a bit of research. Our post is a great place to get started; however, you need to test the product before you decide on a long-term commitment. Here are the basic steps you can take to make a grounded choice for powering your practice with patient engagement software.

Check for compliance: HIPAA, GDPR

For many healthcare organizations looking to adopt third-party medical portal software, regulatory compliance becomes a vital factor for good reasons. Ignoring HIPAA compliance requirements results in severe penalties, with organizations fee enforcement up to $250,000, jail time of up to 5 years, and even lawsuits (civil and criminal). Most providers are aware of this fact and, therefore, strongly emphasize security and regulatory companies. However, double-check all the requirements in your legislation.

Prioritize functionality

When choosing an electronic health software with a patient access system, consider the features that your users will benefit most. If you run a small organization or private practice don’t go for complex all-in-one tools. If your healthcare organization accounts for a large patient base, advanced functionality like telehealth, file sharing, in-depth analytics and detailed reporting will help you take your service to the next level.

Evaluate technical features

Reaching your patients on the devices and platforms of their choice lets you extend your service and increase their engagement with your organization. Complex medical portal software usually suggests the support of standalone mobile apps. They are more effective from a marketing standpoint as they let you send in-app notifications, promotions, and vital information related to your operation or customer healthcare. If you lean towards basic patient management portals, mobile-friendly web availability is also a feasible choice.

Review integration capabilities

Extensive integration capabilities are a soft spot for many patient portal vendors. However, it’s an important factor which you should consider for future growth. Ensure you choose a solution that can integrate with your existing systems and adapt to evolving healthcare needs.

Read reviews and ratings

Go for software review and rating platforms like Capterra and GetApp for honest feedback on the patient portal of your choice. Their beauty is that all reviews are detailed and verified there, so you can match the use case and see if the portal software applies to your medical organization.

Sign up for free trial

The pricing options for most medical portal software are flexible and depend on the number of users and patients you target. Before making a year-term signup commitment, make the best use of a free trial or request one. The minimum one is a 7-day period. However, some providers let you evaluate their product within a month or longer. Feel free to address any issues with the vendor, clarify everything you need, and pay close attention to customer support within this period.

Discover the Opportunities of Tailored Patient Portals 

Patient engagement and better care are among every healthcare organization's most essential and timeless needs. Health and wellness tracking apps, activity tracking apps, and telehealth apps aim to help organizations improve patients' access to quality care while simultaneously alleviating the organization's administrative workload. Patient portal software is no exception. 

At NEKLO, we specialize in custom patient engagement software development to make solutions that fully align with your needs and goals. We prioritize security and regulatory compliance to deliver software that's market-ready and protects your patient's health information.

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Whether you want to enhance patient engagement and comply with regulatory standards, our custom solutions ensure seamless functionality and user-friendly experiences. Get in touch for a free consultancy.